One trick I've used with success is to use a rag, shop towel, bath towel, etc. as an extra layer of protection between my hands and the line. Used T-shirt works well. The idea is that you still have a decent grip but there isn't nearly so much friction against the surface of your skin. I'm not a fan of gloves when it comes to handling line (even when racing) though I have tried them while splicing and the rag method seems to work better for me.